A disorder marked by demyelination and inflammation of peripheral nerves and motor fibers of ventral roots.

Muscle weakness in the extremities is a symptom of this disorder.

Guillain-Barre Syndrome is a form of immune-mediated condition resulting in rapidly progressing weakness with possible paralysis of the extremities and occasionally even of the respiratory and facial muscles.

This demyelinating disease is often associated with a recent respiratory or gastrointestinal infection; the muscle weakness reaches its greatest point within 3 weeks of the initial symptoms and 5% of the afflicted individuals die of the disease.

Plasmapheresis and administration of autoimmune globulin are treatments of choice.