- These are infectious diseases transmitted by prions
- Known as TSE (Transmissible Spongiform Encephalopathy), CJD (Creutzfeldt-Jakob Disease), and Kuru
- These diseases are transmitted by inoculation, cannibalism, and genetic inheritance.
- PrP --> PrPSc --> Fibrils
- PrP is non-infectious and PrPSc is infectious
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