Caused by vitamin C

Vitamin C is a cofactor for prolyl hydroxylase

Symptoms include ulceration of gums and hemorrages

A deficiency in vitamin C, which is marked by skeletal anomolies and hemorrhages.

Ascorbic acid is required in the hydroxylation of lysines and prolines in collagen

Ascorbic acid facilitates in the absorption of dietary iron from the intestine

Ascorbic acid is important in carnitine synthesis (requires Fe(II))

Ascorbic acid is required for the synthesis of norepinephrine from dopamine

Ascorbic acid is a water-soluble antioxidant.

Deficiency in ascorbic acid leads to scurvy. Scurvy is characterized by sore, spongy gums, loose teeth, fragile blood vessels, swollen joints, and anemia.

Collagen quality will be poor in vitamin C deficiency.